COMPOSTOS HETEROCÍCLICOS FUSIONADOS COMO MODULADORES DO CANAL DE IÕES

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专利权人:

INC.;GILEAD SCIENCES

发明人:

THAO PERRY,BRITTON CORKEY,GREGORY NOTTE,ELFATIH ELZEIN,ROBERT JIANG,RAO KALLA,TETSUYA KOBAYASHI,DMITRY KOLTUN,XIAOFEN LI,ERIC PARKHILL,JEFF ZABLOCKI

申请号：

PT10737724

公开号：

PT2464645T

申请日:

2010.07.26

申请国别(地区):

PT

年份:

2017

代理人:

摘要：

The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein W1, W2, W3, R1, Q, X1, X2 and X3 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.

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