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COMPOSES DE TRIAZOLOPYRIDINONE COMME MODULATEUR DE CANAL IONIQUE
专利权人:
GILEAD SCIENCES; INC.
发明人:
KOBAYASHI, TETSUYA,KOLTUN, DMITRY,NOTTE, GREGORY,PARKHILL, ERIC,ZABLOCKI, JEFF
申请号:
CA2802288
公开号:
CA2802288A1
申请日:
2011.06.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, R4, and R5 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
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