A device for introducing a material into a body cavity is shown. The device includes a catheter with a distal tip. A first lumen (250) extends through the catheter. The catheter is configured to form a mist from liquid passed through the first lumen, for example including a misting nozzle (130) in fluid communication with the first lumen and configured to provide a mist from a flow of liquid through the first lumen. An inflatable balloon (140) may be included on the catheter to allow the user to isolate the portion of the body in which the material is introduced. Additional described features can provide for controlled deflection of a distal region of the catheter, guidewire or guide loop tool lumens, first and second misting nozzles on the catheter, and delivery apparatuses including the catheter devices coupled or that can be coupled to endoscopes such as bronchoscopes. Methods of use of the catheter devices and delivery apparatuses are also described.
