Recombinant protein coding RNA useful for mitochondrial dysfunction, its composition and method of preparation thereof.

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专利权人:

发明人:

SAMIT ADHYA INDIA

申请号：

IN2034/DEL/2008

公开号：

IN299427B

申请日:

2008.08.28

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention provides compositions and methods for using correctional RNA, with a proteinaceous carrier, to stimulate respiration of the cells, tissues, organs or the whole organism of normal or diseased subjects. In one embodiment of the invention, the signal-tagged correctional RNA is one or more protein-coding RNAs (pcRNA) that encode one or more of human mitochondrial proteins. The invention specifically provides a broad-spectrum formulation applicable to a wide variety of disorders that are associated with mitochondrial mutations. WO2010023544A1

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