A compound of formula (Ia) or (Ib): ** Formula ** including any stereochemically isomeric form thereof, wherein p is an integer equal to 1, 2, 3 or 4； n is an integer equal to 10 or 1； with the proviso that if n is 2 then both R5 substituents are attached to the same carbon atom of the piperidine residue； R1 is hydrogen, cyano, cyanoC1-6alkyl, formyl, carboxyl, halo, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, polyhaloalkylC1-6alkyl, hydroxy, C1-6alkyloxyC1-6alkyloxyC1-6alkyloxy 6, C1-6alkylthioC1-6alkyl, -C>； = N-OR11, amino, mono- or di (C1-6alkyl) amino, aminoC1-6alkyl, mono- or di (C1-6alkyl aminoC1-6alkyl, C1-6alkylcarbonylaminoalkylC1- 6, R9bR10bN-C (>； = O) -, arylalkylC1-6, arylcarbonyl, R9aR10aNalkylC1-6, di (aryl) alkylC1-6, aryl, cycloalkylC3-6, R9aR10aN-, R9aR10aN-C (>； O) - -4-S (>； = O) 2-, or Het； R2 is hydrogen, C1-6alkyloxy, aryl, aryloxy hydroxy, mercapto, C1-6alkyloxyC1-6alkyloxy, C1-6alkylthio, mono- or ** Formula ** di (C1-6alkyl) amino, amino, pyrrolidine or a radical of the formula in where Y is CH2, O, S, NH or NalkylC1-6； R3 is hydrogen, halo, C1-6alkyl, aryl or Het； R4 is aryl1 or Het； R5 is aryl, arylaC1-6alkyl, C3-6cycloalkyl, cycloalkylC3-6alkylC1-6, Het, Het-C1-6alkyl, C1-6alkyl, hydroxyalkylC1-6alkyl, aminoC1-6alkyl, mono- or di (C1-4alkyl) -alkylC1-6. , aryl-NH-C1-6alkyl, Het-NH-C1-6alkyl, C2-6alkenyl or halo； R6 is hydrogen, C1-6alkyl, arylalkylC1-6, Het1, Het1C1-6alkyl or -C (>； = NH) -NH2； R7 is hydrogen or C1-6alkyl； R8 is oxo； or R7 and R8 together form the radical -CH>； = CH-N>； =； R9a and R10a together with the nitrogen atom to which they are attached form a radical selected from the group consisting of pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, 4-thiomorpholinyl, 2,3-dihydroisoindole-1-yl, thiazolidin-3-yl, 1,2,3,6-tetrahydropyridyl, hexahydro-1H-azepinyl, hexahydro-1H-1,4-diazepinyl, hexahydro-1,4-oxazepinyl, 1,2,3,4-tetrahydroisoquinolin-2-yl, pyrrolinyl, pyrrolyl, imidazolidinyl, pyrazolidinyl, 2-imidazolin
