The invention relates to a preparation and to a method for inducing, enhancing or accelerating the skin pigmentation, both for mere cosmetic purposes and for therapeutic purposes, for the therapy and/or prophylaxis of dischromic pathologies of the skin. The method is based on the application of a topical skin preparation containing NGF (Nerve Growth Factor), so as to obtain an intensification of the skin color or the re-pigmentation of de-pigmented epidermal areas following vitiligo or other hypopigmentary skin diseases.The preparation of NGF and the connected method can also be used in combination with other therapies known for the treatment of skin discoloration, such as the application of topical corticosteroids, activated vitamin D and/or activated vitamin D3, or phototherapy alone or in combination with photosensitizing agents, in particular psoralens.
