The invention concerns a device (1) for taking samples of biological tissue for cytological/histological tests, which comprises a needle (2) which can move from a non-working position to a working position, and vice versa, to take a sample of tissue to be examined the device (1) is configured to be connected to a distal portion (26) of an instrument (25) designed to perform clinical tests once connected to the distal portion (26) of the instrument (25) designed to perform clinical tests, the device (1) defines a working means located outside the instrument (25).
