A device for taking samples of tissue for cytological/histological tests using an instrument, or endoscope, including a body provided with means for reversible association with the distal portion of the instrument said body housing:a needle for taking a tissue sample, movable between a proximal back, non-operating position, inside the body and a distal, operating position partly outside the body, for penetrating the tissue to be tested said needle including a portion designed to form a seat for receiving said tissue sample. The device is also provided with first control means associated with said needle, being positioned and slidable inside said analysis instrument, and designed to allow the movement, in both directions, between said proximal position and said distal position.
