ASTRAZENECA INVESTMENT (CHINA) CO., LTD;ASTRAZENECA AB
发明人:
DENG, Chaoyi
申请号:
CNCN2016/077095
公开号:
WO2017/161518A1
申请日:
2016.03.23
申请国别(地区):
CN
年份:
2017
代理人:
摘要:
A crystalline form of 2, 2-difluoro-N- [ (1R, 2S) -3-methyl-1- { [1- (1-methyl-6-oxo-1, 6-dihydropyridin-3-yl) -1H-indazol-5-yl] oxy} -1-phenylbutan-2-yl] propanamide (form C), pharmaceutical compositions containing it and its use in therapy.L'invention concerne une forme cristalline de 2, 2-difluoro-N- [ (1R18,2S)-3-méthyl-1-{[1- (1-méthyl-6-oxo -1,4-dihydropyridin-3-yl)-3-méthyl-1-{[1- (1-méthyl-6-oxo -1, 6-dihydropyridin-3-yl)) -1 H-indazol-5-yl] oxy}-1-phénylbutan-2-yl] propanamide (forme C), des compositions pharmaceutiques la contenant et son utilisation en thérapie.