STABLE AND SOLUBLE FORMULATIONS OF RECEPTOR TYROSINE KINASE INHIBITORS, AND METHODS OF PREPARATION THEREOF

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专利权人:

INC.;FORSIGHT VISION4

发明人:

HORVATH, JUDIT,ASTAFIEVA, IRINA,ERICKSON, SIGNE,FARINAS, KATHLEEN, COGAN

申请号：

SG11201700943T

公开号：

SG11201700943TA

申请日:

2015.08.06

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib； methods of preparation thereof； and use of the disclosed formulations in sustained delivery of the active agent to a target site. The disclosure further relates to methods of converting one polymorphic Form of a TKI to another polymorphic Form and/or an amorphous form.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/