Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof

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专利权人:

ForSight Vision4; Inc.

发明人:

Judit Horvath,Irina Astafieva,Signe Erickson,Kathleen Cogan Farinas

申请号：

US14819682

公开号：

US09474756B2

申请日:

2015.08.06

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib； methods of preparation thereof； and use of the disclosed formulations in sustained delivery of the active agent to a target site. The disclosure further relates to methods of converting one polymorphic Form of a TKI to another polymorphic Form and/or an amorphous form.

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中国工程科技知识中心

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http://www.ckcest.cn/home/