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MÉTHODE ET COMPOSITION POUR LE TRAITEMENT DE TROUBLES GASTRO- SOPHAGIENS
专利权人:
PH SCIENCE HOLDINGS INC
发明人:
BURNS, ROBERT,GUROL, ISMAIL,LOYD, STEVEN
申请号:
EP13838573
公开号:
EP2919856A4
申请日:
2013.09.18
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
An orally administered composition that includes least one alkaline agent with a pH of at least 9.0 to 12.0, mixed in an aqueous vehicle with relatively high surface tension, high viscosity and lateral adhesion properties. When mixed, a low water soluble emulsion is formed that evenly coats and partially adheres to the lower section of the esophagus and the LES and forms a relatively long acting, protective barrier and partially neutralizes gastric acid. In one embodiment, the alkaline agent is potassium hydroxide and the aqueous vehicle is made of hydroxypropyl methyl cellulose, polyethylene glycol or ethylene glycol and additional thickener agents capable of withstanding high pH environments, such as xanthan gum, croscarmellose sodium, and microcrystalline cellulose. Additional organoleptic agents, such as gum Arabic and polyethylene glycol, flavorings, such as sodium chloride, acesulfame potassium, sodium saccharine, and mint, and stabilizers such as colloidal silica made be added.
来源网站:
中国工程科技知识中心
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