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PHARMACEUTICAL FORMULATIONS FOR THE ORAL DELIVERY OF PEPTIDE OR PROTEIN DRUGS
专利权人:
发明人:
申请号:
EP15788340.6
公开号:
EP3204045A1
申请日:
2015.10.07
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to improved pharmaceutical formulations, uses and methods for the oral delivery of peptide or protein drugs with advantageously high bioavailability, safety and cost-effectiveness. In particular, the invention provides a peptide or protein drug having a molecular weight of equal to or less than about 50 kDa for use as a medicament, wherein said peptide or protein drug is to be administered orally in combination with a pharmaceutically acceptable copper salt/complex and/or a pharmaceutically acceptable zinc salt/complex, and with a pharmaceutically acceptable reducing agent. The invention also provides a pharmaceutical composition comprising: a peptide or protein drug having a molecular weight of equal to or less than about 50 kDa a pharmaceutically acceptable copper salt/complex and/or a pharmaceutically acceptable zinc salt/complex and a pharmaceutically acceptable reducing agent.
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中国工程科技知识中心
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