GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
Christopher B. HOPSON,David J. KILIAN,Patrick A. MAYES,Sapna YADAYILLI,Niranjan YANAMANDRA
申请号:
US16620782
公开号:
US20200181275A1
申请日:
2018.06.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides methods of treating cancer in a patient in need thereof, the method comprising administering to the patient an effective amount of an agent directed to human ICOS and an effective amount of an agent directed to human OX40 sequentially. The present invention also provides an anti-ICOS antibody or antigen binding fragment thereof and an anti-OX40 antibody or antigen binding fragment thereof for sequential use in treating cancer in a human in need thereof.