Frank Himmelsbach;Matthias Eckhardt;Bradford S. Hamilton
发明人:
Matthias Eckhardt,Bradford S. Hamilton,Frank Himmelsbach
申请号:
US13054949
公开号:
US08309597B2
申请日:
2009.07.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases.