A medical air mattress has a mattress body and an upper bedspread. The mattress body is formed by multiple air cells including independent air cells parallelly arranged as an air cell row. The upper bedspread covers the mattress body. The independent air cells are connected to the independent deflating unit to be deflated independently. When the patient needs to use the bedpan, the independent air cells are deflated to form a recess for receiving the bedpan so that the patient needs not to move.