The present invention relates to a pharmaceutical composition for the prevention or treatment of degenerative neurological brain disorders and, more specifically, relates to a pharmaceutical composition for the prevention or treatment of degenerative neurological brain disorders, such as Parkinsons disease, Alzheimers dementia (senile dementia), stroke, Lou Gehrigs disease, Picks disease, Creutzfeldt-Jakob disease, Huntingtons disease, progressive supranuclear palsy, spinocerebellar degeneration, cerebellar atrophy, multiple sclerosis, post-traumatic stress disorder and amnesia, the composition containing a paraben compound as an active ingredient having effects that are useful in combating oxidation to remove active oxygen, suppressing cell-death, improving impaired movement, and enhancing declining memory.