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SUSTAINED RELEASE OF MICROCRYSTALLINE PEPTIDE SUSPENSIONS
专利权人:
MEDICAL RESEARCH COUNCIL TECHNOLOGY
发明人:
ROMANO DEGHENGHI,FRANCOIS BOUTIGNON
申请号:
PT10003046
公开号:
PT2198888T
申请日:
2002.08.27
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
The invention relates to a method of preventing gel formation of a hydrophobic peptides by contacting the hydrophobic peptide with a counter-ion in an amount and at a molar ratio sufficient to provide a fluid, milky microcrystalline aqueous suspension of the peptide without formation of a gel. The invention also relates to a fluid, milky microcrystalline aqueous suspension of a hydrophobic peptide and a counter-ion in water, wherein the peptide and counter-ion are present in amounts and at a molar ratio sufficient to form, upon mixing, the suspension without formation of a gel.
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