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Sustained release of microcrystalline peptide suspensions
专利权人:
Romano Deghenghi
发明人:
Romano Deghenghi,Francois Boutignon
申请号:
US13224105
公开号:
US08415300B2
申请日:
2011.09.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A fluid, milky microcrystalline aqueous suspension of a peptide or peptidomimetic and a counter-ion of a strong proton donor in water, wherein the peptide or peptidomimetic and counter-ion are present in amounts and at a molar ratio sufficient to form the suspension upon mixing and without formation of a gel. Also, lyophilized compositions that include a dried suspension, methods of making the lyophilized composition, methods of preparing the suspension, and sustained release formulations prepared by the methods.
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