Alastair Morgan Mackay;Mark F. Pittenger;Stephen L. Gordon;Bradley J. Martin
发明人:
Mark F. Pittenger,Stephen L. Gordon,Alastair Morgan Mackay,Bradley J. Martin
申请号：
US13369880
公开号：
US20120207716A1
申请日:
2012.02.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.
