Alastair Morgan Mackay;Mark F. Pittenger;Stephen L. Gordon
发明人:
Mark F. Pittenger,Stephen L. Gordon,Alastair Morgan Mackay
申请号:
US12725867
公开号:
US08158120B2
申请日:
2010.03.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.