A kind of method of inhibition Tyrosine ferment translation of what is closed in system of the present invention, and it includes the translations for inhibiting the segment as coded by Tyrosine ferment First ray area TIF-1 or the second sequence area of Tyrosine ferment TIF-2 in cell. The nucleic acid molecules and medical composition that the present invention also closes a kind of method for inhibiting Mai Laning melanin (melanin) generation of what, can inhibit the translation of Tyrosine ferment or Mai Laning melanin production.本發明係關於一種抑制酪胺酸酵素轉譯之方法，其包含抑制細胞中由酪胺酸酵素第一序列區TIF-1或酪胺酸酵素第二序列區TIF-2所編碼片段之轉譯。本發明亦關於一種抑制麥拉寧黑色素(melanin)生成之方法、可抑制酪胺酸酵素轉譯或麥拉寧黑色素生成之核酸分子及醫藥組合物。
