經修飾之脂質化鬆弛素B鏈胜肽及其醫療用途农业专利-农业学术服务平台

发明人:: DUCLOS, OLIVIER,杜克洛　艾利维亚,杜克洛　艾利維亞,ILLIANO, STEPHANE,艾里安诺　史蒂芬妮,艾里安諾　史蒂芬妮,MALLART, SERGIO,马拉特　赛尔吉欧,馬拉特　賽爾吉歐,MINOLETTI-HOCHEPIED, CLAIRE,米诺莱帝　荷契皮德　克莱尔,米諾萊帝　荷契皮德　克萊爾,BIANCHI, ELISABETTA,比安奇　伊莉莎白,比安奇　伊莉莎白

摘要：: The present invention relates to a biologically active single chain Relaxin peptide having the following formula (I): Nter-Ac-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-X31-X32-X33-NH2-Cter or a salt or solvate thereof.It also concerns a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament.本發明係關於具有下式(I)之生物活性單鏈鬆弛素胜肽：Nter-Ac-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-X31-X32-X33-NH2-Cter或其鹽或溶劑化物。其亦關於包括至少一種本發明胜肽之醫藥組成物，以及其作為醫藥品用途之此胜肽或此醫藥組成物。