MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE

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专利权人:

Sanofi

发明人:

Denis Brasseur,Olivier Duclos,Stéphane Illiano,Sergio Mallart,Claire Minoletti-Hochepied,Frank Marguet,Elisabetta Bianchi,Raffaele Ingenito,Paola Magotti,Alessia Santoprete

申请号：

US16264547

公开号：

US20190233493A1

申请日:

2019.01.31

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention relates to a biologically active single chain Relaxin peptide having the following formula (I):Nter-Ac-(E)a-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-R-(X32)b-(X33)c-(K)d-(X35)e-(gE)f-X37-Cter；or a salt or solvate thereof.It also concerns a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament.

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中国工程科技知识中心

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http://www.ckcest.cn/home/