Joseph M. Fox;Matthew Hassink;Melissa Blackman;Zibo Li;Peter S. Conti;Ramajeyam Selvaraj
发明人:
Joseph M. Fox,Matthew Hassink,Melissa Blackman,Zibo Li,Peter S. Conti,Ramajeyam Selvaraj
申请号：
US13811568
公开号：
US10434197B2
申请日:
2011.07.21
申请国别(地区):
US
年份:
2019
代理人:
摘要：
A Diels-Alder adduct of a trans-cyclooctene with a tetrazine is provided, wherein the adduct bears a substituent labeled with a radionuclide. A method of producing a PET or other image of an organ in an animal or human includes forming the Diels-Alder adduct in the animal or human. Trans-cyclooctenes and tetrazines suitable for preparing the adducts are provided.
