Thomas Kennedy Hutton,Peter Jay Seaberg,Christopher C. Kerwood
申请号:
US13262102
公开号:
US08927706B2
申请日:
2010.03.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of forming a sucrose-6-ester includes in sequence the steps of: a) contacting sucrose with a organotin-based acylation promoter in a solvent in the presence of a base selected from amines and basic alkali metal salts b) removing water to form a tin-sucrose adduct and c) contacting the tin-sucrose adduct with an acylating agent to form the sucrose-6-ester. The sucrose-6-ester may then be converted to sucralose.