2- (3,5-bis-trifluoromethyl-phenyl) -N-methyl-N- (6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl) -isobutyramide, its preparation process and its use as well as medicine
Andrew Sleight,Guy Andrew Higgins,Sonia Maria Poli,Theresa Maria Ballard,Torsten Hoffmann
申请号：
BRPI0005616
公开号：
BRPI0005616B1
申请日:
2000.11.28
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
2- (3,5-bis-trifluoromethyl-phenyl) -n-methyl-n- (6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl) -benzamide isobutyramide "<；d>；. The invention relates to the compound of the formula which is 2- (3,5-bis-trifluoromethyl-phenyl) -n-methyl-n- (6-morpholin-4-yl-4-o-tolyl-pyridin-2-one). 3-yl) -isobutyramide. This compound has been found to have a high affinity for the receptor for nk-1 and is therefore useful in treating diseases related to this receptor.patente de invenção: <；b>；"2-(3,5-bis-trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida"<；d>；. a invenção refere-se ao composto da fórmula o qual é a 2-(3,5-bis-trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida. foi verificado que este composto tem uma alta afinidade pelo receptor para nk-1 e é, portanto, útil no tratamento de doenças que se relacionam a este receptor.
