THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK ;Department of Anatomy and Cell Biology - Universit y of Iowa
发明人:
Lin Qiao,Zhu Yibo,Shang Junyi,Zhang Zhixing,Wang Xuejun,Yang Jaeyoung,Wang Cheng,Rotti Pavana G.,Engelhardt John F.,Hao Zhuang
申请号：
US201816012527
公开号：
US2018368743(A1)
申请日:
2018.06.19
申请国别(地区):
美国
年份:
2018
代理人:
摘要：
A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene.
