DEPARTMENT OF ANATOMY AND CELL BIOLOGY - UNIVERSITY OF IOWA;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
Qiao Lin,Yibo Zhu,Junyi Shang,Zhixing Zhang,Xuejun Wang,Jaeyoung Yang,Cheng Wang,Pavana G. Rotti,John F. Engelhardt,Zhuang Hao
申请号：
US16810183
公开号：
US20200196925A1
申请日:
2020.03.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene.
