590587 Disclosed is a fluid transfer assembly with means for connecting to a syringe means for receiving a vial with a closure element. The receiving means is adapted to engage and open the closure element and permit fluid in the vial to be transferred to the syringe from the vial. The connection means comprises an end of the fluid transfer assembly which is open and dimensioned to fit over or in an open end of the syringe which is opposite a needle end of the syringe. The fluid transfers in use from the vial to the syringe under the force of gravity, when the receiving means is located above the connection means.