PRODUCTION OF POLIO VIRUS AT HIGH TITERS FOR VACCINE PRODUCTION

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专利权人:

CRUCELL HOLLAND B.V.

发明人:

LEWIS, JOHN, ALFRED

申请号：

SG2012002705

公开号：

SG177655A1

申请日:

2010.07.08

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

The invention provides a process for the production of polio virus, comprising the steps of: a) providing a serum-free suspension culture of cells, which are PER.C6 cells, b) infecting said cells with polio virus, at a cell density of between 2x106 cells/ml and 15Ox106 cells/ml, and c) harvesting polio virus at a time of between 12 and 48 hours after infection.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/