Michael Aaron Brodney,Elizabeth Mary Beck,Christopher Ryan Butler,Jennifer Elizabeth Davoren,Brian Thomas O'Neill,Brian Thomas ONeill
申请号:
US14695920
公开号:
US20150231144A1
申请日:
2015.04.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compounds of Formula I, and the tautomers thereof, and the pharmaceutically acceptable salts of the compounds and tautomers, wherein the compounds have the structurewherein the variables R1, R2, R3, R4 and x are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.