Michael Aaron Brodney,Elizabeth Mary Beck,Christopher Ryan Butler,Jennifer Elizabeth Davoren,Brian Thomas O'Neill
申请号:
US14325409
公开号:
US09045498B2
申请日:
2014.07.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compounds of Formula I, and the tautomers thereof, and the pharmaceutically acceptable salts of the compounds and tautomers, wherein the compounds have the structurewherein the variables R1, R2, R3, R4 and x are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.