GUDE MARKUS,BOSS CHRISTOPH,BROTSCHI CHRISTINE,HEIDMANN BIBIA,SIFFERLEN THIERRY,WILLIAMS JOSI T.
申请号：
CL2014003294
公开号：
CL2014003294A1
申请日:
2014.12.02
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention relates to compounds of the formula (I) wherein Ar1, R1, R2, R3, R4a, R4b and (R5)n are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.COMPUESTOS DERIVADOS DE BENCIMIDAZOL-PROLINA, ANTAGONISTA DEL RECEPTOR DE OREXINA； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES O TRASTORNOS SELECCIONADOS ENTRE SUEÑO, ANSIEDAD, COGNITIVAS, APETITO, ENTRE OTRAS.
