Chin-Chu Chen,Yen-Lien Chen,Shin-Wei Lin,Yen-Po Chen,Yang-Tzu Shih,Ching-Wen Lin
申请号：
US16391777
公开号：
US20190321420A1
申请日:
2019.04.23
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention discloses uses of treating, preventing or improving bone diseases by Lactobacillus or a composition including the Lactobacillus. The Lactobacillus and compositions can increase the blood calcium concentration, the trabecular bone volume density (BV/TV ratio), the trabecular thickness (Tb.Th), the trabecular number (Tb.N) and the bone mineral density (BMD) of a subject, and reduce trabecular spacing (Tb.Sp) of the subject. Further, the present invention discloses a method for treating a subject diagnosed with a bone disease, comprises steps of identifying the subject having the bone disease, and administering to the subject an effective amount of a composition including at least one of Lactobacillus plantarum GKM3 and Lactobacillus paracasei GKS6, wherein the Lactobacillus plantarum GKM3 is deposited in China General Microbiological Culture Collection Center (CGMCC) with a deposition number of CGMCC 14565 on Aug. 25, 2017, and the Lactobacillus paracasei GKS6 is deposited in CGMCC with a deposition number of CGMCC 14566 on Aug. 25, 2017.
