UTILISATION DE DIANHYDROGALACTITOL EN COMBINAISON AVEC DES RAYONS, POUR TRAITER LE CANCER DU POUMON NON À PETITES CELLULES ET LE GLIOBLASTOME MULTIFORME

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专利权人:

Del Mar Pharmaceuticals

发明人:

BACHA, Jeffrey, A.,BROWN, Dennis, M.,STEINØ, Anne,FOUSE, Shaun

申请号：

EP15858948

公开号：

EP3217970A4

申请日:

2015.11.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The use of dianhydrogalactitol provides a novel therapeutic modality for the treatment of non-small-cell lung carcinoma (NSCLC) and for the treatment of glioblastoma multiforme (GBM). Dianhydrogalactitol acts as an alkylating agent on DNA that creates N7 methylation. Dianhydrogalactitol is effective in suppressing the growth of cancer stem cells and is active against tumors that are refractory to temozolomide； the drug acts independently of the MGMT repair mechanism.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/