BALAN, GAYATRI,CHOU, CHIEN-HUNG,KIM, MUSONG,KIRSCHBERG, THORSTEN A.,LINK, JOHN O.,PHILLIPS, GARY,SAITO, ROLAND D.,SQUIRES, NEIL H.,TAYLOR, JAMES G.,WATKINS, WILLIAM J.,WRIGHT, NATHAN E.
申请号:
CA3029457
公开号:
CA3029457A1
申请日:
2017.06.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to 4,6-diaminoquinazoline derivatives of formula I which are modulators of the Cot (cancer Osaka thyroid) kinase, also known as MAP3K8, EST or Tlp-2, and their use for treating e.g. cancer, diabetes and inflammatory diseases.