4,6-diaminoquinazolines as cot modulators and methods of use thereof

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专利权人:

GILEAD SCIENCES INC.

发明人:

Link, John,Saito, Roland,Taylor, James,Chou, Chien-Hung,Kim, Musong,Phillips, Gary,Watkins, William,Squires, Neil,Kirschberg, Thorsten A.,Balan, Gayatri,Wright, Nathan

申请号：

NZ74917217

公开号：

NZ749172A

申请日:

2017.06.27

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

The invention relates to 4,6-diaminoquinazoline derivatives of formula IIIA which are modulators of the Cot (cancer Osaka thyroid) kinase, also known as MAP3K8, EST or Tlp-2, and their use for treating e.g. cancer, diabetes and inflammatory diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/