ELSOHLY, MAHMOUD A.,MAJUMDAR, SOUMYAJIT,GUL, WASEEM,ASHFAQ, MOHAMMAD KHALID,SUFKA, KENNETH JOSEPH,HARRIS, HANNAH MARIE
申请号:
CA3013037
公开号:
CA3013037A1
申请日:
2017.01.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Biologically active cannabidiol analogs comprising a compound of the formula [ I ] wherein one of R1 or R2 or both is/are the residue of a moiety formed by the reaction of an amino group of the amino acid ester of R1 or R2 or both with a dicarboxylic acid or a dicarboxylic acid derivative and the other R1 or R2 (in the case of the mono) is the residue of a dicarboxylic acid or dicarboxylic acid derivative or Hydrogen (H), (i.e. underivatized), and salts thereof. These CBD analogs are be useful in pain management in oncology and other clinical settings in which neuropathy is presented. Furthermore, these CBD-analogs are useful in blocking the addictive properties of opiates.