PROBLEM TO BE SOLVED: To provide carotenoids or xanthophylls in a micro micellar form that act as a more effective and efficient antioxidant than the case of administering in a crystalline form.SOLUTION: The carotenoids or xanthophylls in a micro micellar form are obtained as micro micelles after melting lutein diacetate or lutein dipropionate in their natural original lipid vegetable matrix, in the presence of lipids, phospholipids, fatty acids, emulsifiers and moisture without containing any of crystalline forms of carotenoids, and are ingested in a dosage between 2 to 50 mg, to provide an absorbed amount of the carotenoid solubilizate which is higher by at least 20% than that of crystalline carotenoids, and to provide a macular pigment deposit which exceeds by at least 10% of macular pigment optical density higher than the deposition obtained by ingesting crystalline lutein, thus prevent tissue degeneration, and UV light damage to skin and the retina.COPYRIGHT: (C)2012,JPO&INPIT【課題】結晶形態で投与する場合より有効で効率的な抗酸化剤として作用する、マイクロミセル形態のカロテノイド又はキサントフィルの提供。【解決手段】いかなる結晶形のカロテノイドも含有せず、脂質、リン脂質、脂肪酸、乳化剤、及び水分の存在下で、天然起源の植物性脂質マトリックス中でルテインジアセテート又はルテインジプロピオネートを溶融させた後にマイクロミセルとして得られ、2~50mgの間の投薬量で摂取されて、結晶カロテノイドより少なくとも20%高いカロテノイド可溶化物の吸収を与え、結晶ルテインの摂取によって得られる沈着より黄斑色素光学濃度で少なくとも10%高い黄斑色素の沈着を与え、組織変性、皮膚及び網膜に対する紫外線障害を防ぐ。【選択図】なし
