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Transdermal absorption system containing donepezil or its salt
专利权人:
デウン ファーマシューティカル カンパニー リミテッド
发明人:
チェ,ヨハン,チャン,ヒチョル,チェ,ヨハン,チャン,ヒチョル
申请号:
JP2016566588
公开号:
JP6405391B2
申请日:
2015.01.12
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
Provided is a transdermal delivery system consisting of a backing layer, a drug-containing matrix layer, and a release layer, wherein the drug-containing matrix layer includes (a) donepezil or a pharmaceutically acceptable salt thereof as an active ingredient, (b) a mixture of high molecular weight polyisobutylene having a weight-average molecular weight ranging from 400,000 to 3,000,000 and low molecular weight polyisobutylene having a weight-average molecular weight ranging from 25,000 to 300,000 as an adhesive, and (c) a permeation enhancer in not more than 3% by weight based on the total weight of the drug-containing matrix layer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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