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INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE 1 ENZYME
专利权人:
ABBOTT LABORATORIES
发明人:
JUDD, ANDREW S,MULHERN, MATHEW M,IYENGAR, RAJESH R,KYM, PHILIP R,SOUERS, ANDREW J
申请号:
NZ58066008
公开号:
NZ580660A
申请日:
2008.04.30
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein are compounds of formula (I), wherein G1 is phenyl or pyridinyl, and the other substituents are as defined within the specification, processes for its preparation and uses thereof. Said compounds are useful as inhibitors of diacylglycerol O-acyltransferase type 1 (DGAT-1) enzyme and are therefore useful in the treatment of diseases related thereof, such as type 2 diabetes, obesity, elevated plasma triglycerides, metabolic syndrome, non-alcoholic steatohepatitis, and non-alcoholic fatty liver disease.
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中国工程科技知识中心
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