GEOFFREY, DUKE CLARKE EDWARD,GRATTAN, TIMOTHY JAMES,BURNETT, IAN
申请号：
MYPI 2011000429
公开号：
MY151230A
申请日:
2009.07.29
申请国别(地区):
MY
年份:
2014
代理人:
摘要：
THE PRESENT INVENTION IS DIRECTED TO A NOVEL METHOD FOR REDUCING INTRAPATIENT VARIABILITY IN PHARMACEUTICALLY ACTIVE AGENT WHICH IS SUITABLY NOT ABSORBED IN THE STOMACH, SUCH AS PARACETAMOL, CONTAINING FORMULATIONS IN PATIENTS HAVING GASTRIC DYSMOTILITY, OR A METHOD OF IMPROVING ANALGESIA IN A DIABETIC PATIENT, OR IMPROVING ABSORPTION OF AN ACTIVE AGENT IS A PATIENT WITH GASTRIC DYSMOTILITY, WHICH METHODS COMPRISES ADMINISTERING ORALLY TO SAID PATIENT IN NEED THEREOF A PHARMACEUTICAL DOSAGE FORM COMPRISING A FIRST ACTIVE AGENT, CALCIUM CARBONATE, AT LEAST ONE FIRST BINDING AGENT, AND AT LEAST ONE DISINTEGRATING AGENT AS INTRAGRANULAR COMPONENTS IN THE FORM OF A GRANULATE, AND AS AN EXTRAGRANULAR COMPONENT AT LEAST ONE HYDROPHILIC COLLOID, AN OPTIONALLY A SECOND BINDING AGENT, CALCIUM CARBONATE, A SUPER DISINTEGRANT, AND A SECOND ACTIVE AGENT.
