AbstractTo find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group； B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group； Rl represents a hydrogen atom or a Cl-C3 alkyl group； R2 represents a hydrogen atom or a Cl-C3 alkyl group； R3 represents a Cl-C6 alkyl group, a C3-C10 cycloalkyl group, a Cl-C3 alkoxy Cl-C3 alkyl group, or a Cl-C3 hydroxyalkyl group； R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom； n represents an integer of 1 to 4； and X represents methylene, -0-, -NH-, -N(C1-C3 -C(=0)-, -S-, -S(0)-, -S(02)-, or asingle bond.
