Max-Delbruck-Centrum fur Molekulare Medizin;Board of Regents, The University of Texas System; The University of Texas System;Board of Regents
发明人:
Schunck, Wolf-Hagen,Muller, Dominik,Fischer, Robert,Wallukat, Gerd,Konkel, Anne,Falck, John Russell
申请号:
AU2015208416
公开号:
AU2015208416A1
申请日:
2015.01.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.