ANDREW IHOR KORYTKO,BRIAN JOHN ONDEK,ROHN LEE JUNIOR MILLICAN
申请号：
BRPI0910118
公开号：
BRPI0910118A2
申请日:
2009.03.17
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention relates to glucagon receptor polypeptide antagonists which inhibit the binding of the hormone glucagon to its receptor. More particularly, the present invention relates to high affinity glucagon receptor antibodies or Fab fragments thereof that inhibit binding of glucagon to its receptor and their use in the treatment or prevention of type 2 diabetes (NIDDM) and related disorders in mammalian species.
