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Spatially offset raman spectroscopy of layered soft tissues and applications of same
专利权人:
发明人:
Anita Mahadevan-Jansen,Matthew D. Keller,Mark C. Kelley
申请号:
US14620846
公开号:
US09289130B2
申请日:
2015.02.12
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention in one aspect relates to a method for discriminating soft biological tissues. The method includes illuminating soft biological tissues at at least one first spot with light collecting Raman scattering light scattered from the soft biological tissues at at least second spot in response to illumination by the light, wherein the at least second spot is away from the at least one first spot so as to define a source-detection (S-D) offset distance therebetween obtaining a spatially offset Raman spectrum from the collected light, wherein the spatially offset Raman spectrum is associated with a depth of the soft biological tissues at which the Raman light is scattered identifying tissue signatures from the spatially offset Raman spectrum and determining whether the soft biological tissues have a layered structure from the tissue signatures from the spectrum.
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