1. An immunogenic composition comprising a polypeptide subfamily B LP2086 (fHBP), prepared so that the efficiency of a polypeptide subfamily B LP2086 (fHBP) stable over vremeni.2. An immunogenic composition comprising a detergent and a polypeptide subfamily B LP2086 (fHBP) in a molar ratio of detergent: protein ratio of less 10: 1.3. An immunogenic composition according to claim 1 or 2, wherein at least 50% efficiency polypeptide subfamily B LP2086 (fHBP) is maintained for at least 1 month, 2 months, 3 months, 4 months, 5 months, 6 months, 9 months, 12 months, 18 months, 24 months, 30 months, 36 months, 42 months, 48 months, 54 months or 60 mesyatsev.4. An immunogenic composition according to claim 1 or 2, further comprising a polypeptide subfamily A LP2086 (fHBP) .5. The immunogenic composition of claim 1, further comprising detergent.6. An immunogenic composition according to claim 1 or 2, wherein the molar ratio of detergent: protein is from about 0.5: 1 to about 10: 1.7. The immunogenic composition of claim 6, wherein the molar ratio of detergent: protein is from about 1: 1 to about 5: 1.8. The immunogenic composition of claim 7, wherein the molar ratio of detergent: protein is from about 1.4: 1 to about 4.2: 1.9. The immunogenic composition of claim 8, wherein the molar ratio of detergent: protein ratio of about 2.8: 1.10. An immunogenic composition according to claim 1 or 2, wherein the amount of detergent is sufficient to reduce binding of the polypeptide to silicon in konteynere.11. The immunogenic composition of claim 10, wherein the container is a syringe or flakon.12. An immunogenic composition according to claim 1 or 2, wherein the detergent is a nonionic detergent.13. The immunogenic composition of claim 12 wherein the detergent is n
