A device is disclosed for generating controlled pneumatic pressure to a human body to achieve mucus clearance from the pulmonary system. Controlled pneumatic pressure consisting of individual vibratory pressure and constrictive pressure variations are generated and applied to the thorax to promote mucus clearance. The vibratory pressure variation is channeled to a pressure receiver secured to the upper thorax of the body, and the constrictive pressure variation is channeled to a pressure receiver secured to the lower thorax of the body. The vibratory pressure variation serves to loosen the mucus, while the constrictive pressure variation provides the motive force that promotes mucus expulsion from the pulmonary system.