The present invention aims to provide a highly functional toothpaste composition that can achieve the effects of not only preventing tooth decay, but also removing halitosis, removing inflammation, alleviating oral diseases, treating sensitive teeth, and whitening teeth using natural materials.To this end, the present invention comprises: Curcuma longa L.; natural organic sulfur; mint extract; red ginseng fermentation extract; and antibacterial combined extract made by extracting at least one from the group consisting of green tea, dried orange peel, Houttuynia cordata Thunb., Rumex crispus, licorice, and Mori Cortex Radicis.